Comet Assay

Genotoxic potential of BM-21, an aqueous-ethanolic extract from Thalassia testudinum marine plant. | [Potencial genotóxico del BM-21, un extracto hidroalcohólico obtenido de la planta marina Thalassia testudinum]

Genotoxicity / Genotoxicology / Comet Assay / Ames Test / Genotoxicología / Genotoxicity of medicinal plants / Micronucleus Assay / SOS Chromotest / Genotoxicity of medicinal plants / Micronucleus Assay / SOS Chromotest

Comet-FISH using peptide nucleic acid probes detects telomeric repeats in DNA damaged by bleomycin and mitomycin C proportional to general DNA damage

DNA damage / DNA repair / DNA / Humans / Mutagenesis / Nucleic acid hybridization / Peptide Nucleic Acids / Comet Assay / Cell nucleus / Time Factors / Telomere / Bleomycin / Mutagens / Nucleic Acid / Mitomycin / DNA fragmentation / Nucleic acid hybridization / Peptide Nucleic Acids / Comet Assay / Cell nucleus / Time Factors / Telomere / Bleomycin / Mutagens / Nucleic Acid / Mitomycin / DNA fragmentation

The protective effects of guaraná extract (Paullinia cupana) on fibroblast NIH-3T3 cells exposed to sodium nitroprusside

Oxidative Stress / DNA damage / Antioxidants / Caffeine / Mice / Nitric oxide / Animals / High Pressure Liquid Chromatography / Comet Assay / Plant extracts / Food Sciences / Human Fibroblasts / Food and Chemical Toxicology / Catechin / Theobromine / Nitric oxide / Animals / High Pressure Liquid Chromatography / Comet Assay / Plant extracts / Food Sciences / Human Fibroblasts / Food and Chemical Toxicology / Catechin / Theobromine

Intracellular iron, but not copper, plays a critical role in hydrogen peroxide-induced DNA Damage

Calcium / DNA damage / Transition-Metal Oxides / Humans / Copper / Iron / Hydrogen Peroxide / Comet Assay / Time Factors / Chelating Agents / Oxidation-Reduction / Biochemistry and cell biology / Glucose Oxidase / Iron / Hydrogen Peroxide / Comet Assay / Time Factors / Chelating Agents / Oxidation-Reduction / Biochemistry and cell biology / Glucose Oxidase

Genotoxic Evaluation of Mikania laevigata Extract on DNA Damage Caused by Acute Coal Dust Exposure

Nutrition and Dietetics / Coal / DNA damage / Liver / Femur / Animals / Blood / Male / Bone marrow / Comet Assay / Plant extracts / Rats / Hepatocytes / Medicinal / Group / Wistar Rats / Food Sciences / Medicinal Food / Dust / Organic Compound / Environmental Exposure / Control Group / Animals / Blood / Male / Bone marrow / Comet Assay / Plant extracts / Rats / Hepatocytes / Medicinal / Group / Wistar Rats / Food Sciences / Medicinal Food / Dust / Organic Compound / Environmental Exposure / Control Group

Genotoxic Evaluation of Mikania laevigata Extract on DNA Damage Caused by Acute Coal Dust Exposure

Nutrition and Dietetics / Coal / DNA damage / Liver / Femur / Animals / Blood / Male / Bone marrow / Comet Assay / Plant extracts / Rats / Hepatocytes / Medicinal / Group / Wistar Rats / Food Sciences / Medicinal Food / Dust / Organic Compound / Environmental Exposure / Control Group / Animals / Blood / Male / Bone marrow / Comet Assay / Plant extracts / Rats / Hepatocytes / Medicinal / Group / Wistar Rats / Food Sciences / Medicinal Food / Dust / Organic Compound / Environmental Exposure / Control Group

The protective effects of guaraná extract (Paullinia cupana) on fibroblast NIH-3T3 cells exposed to sodium nitroprusside

Oxidative Stress / DNA damage / Antioxidants / Caffeine / Mice / Nitric oxide / Animals / High Pressure Liquid Chromatography / Comet Assay / Plant extracts / Food Sciences / Human Fibroblasts / Food and Chemical Toxicology / Catechin / Theobromine / Nitric oxide / Animals / High Pressure Liquid Chromatography / Comet Assay / Plant extracts / Food Sciences / Human Fibroblasts / Food and Chemical Toxicology / Catechin / Theobromine

A model of sensitivity: 1,3-butadiene increases mutant frequencies and genomic damage in mice lacking a functional microsomal epoxide hydrolase gene

DNA damage / Biological Sciences / Environmental Sciences / Mutation / Mice / Animals / Drug Resistance / Comet Assay / Environmental / Animals / Drug Resistance / Comet Assay / Environmental

Acacia salicina extracts protect against DNA damage and mutagenesis in bacteria and human lymphoblast cell K562 cultures

Nutrition and Dietetics / Nutrition / DNA damage / Antioxidants / Humans / Mutagenesis / Salmonella Typhimurium / Acacia / Hydrogen Peroxide / Comet Assay / Ames Test / Integrated Approach / Antioxidant Activity / Ethyl Acetate / Plant extracts / Superoxide Anion / Xanthine Oxidase / Plant Leaves / Mutagenesis / Salmonella Typhimurium / Acacia / Hydrogen Peroxide / Comet Assay / Ames Test / Integrated Approach / Antioxidant Activity / Ethyl Acetate / Plant extracts / Superoxide Anion / Xanthine Oxidase / Plant Leaves

Effects of Agelas oroides and Petrosia ficiformis crude extracts on human neuroblastoma cell survival

Oncology / Reactive Oxygen Species / Animals / Cell Death / Neuroblastoma / Comet Assay / Ascorbic Acid / Cell Survival / Comet Assay / Ascorbic Acid / Cell Survival

Acacia salicina extracts protect against DNA damage and mutagenesis in bacteria and human lymphoblast cell K562 cultures

Nutrition and Dietetics / Nutrition / DNA damage / Antioxidants / Humans / Mutagenesis / Salmonella Typhimurium / Acacia / Hydrogen Peroxide / Comet Assay / Ames Test / Integrated Approach / Antioxidant Activity / Ethyl Acetate / Plant extracts / Superoxide Anion / Xanthine Oxidase / Plant Leaves / Mutagenesis / Salmonella Typhimurium / Acacia / Hydrogen Peroxide / Comet Assay / Ames Test / Integrated Approach / Antioxidant Activity / Ethyl Acetate / Plant extracts / Superoxide Anion / Xanthine Oxidase / Plant Leaves

Donor cornea transfer from Optisol GS to organ culture storage: a two-step procedure to increase donor tissue lifespan

Stem Cells / Oxidative Stress / Cornea / Cryopreservation / DNA damage / Humans / Female / Male / Differentiation / Organ Preservation / Lipid peroxidation / Clinical Sciences / Comet Assay / Middle Aged / Optometry and Ophthalmology / Time Factors / Organ Culture / Biological markers / Cell Proliferation / Neurosciences / Enzyme Linked Immunosorbent Assay / Organ Preservation Solutions / Humans / Female / Male / Differentiation / Organ Preservation / Lipid peroxidation / Clinical Sciences / Comet Assay / Middle Aged / Optometry and Ophthalmology / Time Factors / Organ Culture / Biological markers / Cell Proliferation / Neurosciences / Enzyme Linked Immunosorbent Assay / Organ Preservation Solutions

Molecular epidemiology studies of carcinogenic environmental pollutants

Genetics / Polymorphism / Environmental Monitoring / Air pollution / DNA damage / DNA repair / Environmental Pollution / Czech Republic / Molecular Epidemiology / Humans / Mutation / Polycyclic Aromatic Hydrocarbon / Carcinogens / Enzyme / Reviews / Comet Assay / Polycyclic aromatic hydrocarbons (PAHs) / Fluorescent In-Situ Hybridisation / Neoplasms / Particulate Matter / Biological markers / Environmental Pollutants / Oxidative Dna Damage / Genetic Susceptibility / Cancer Risk / Organic Compound / Environmental Exposure / DNA repair / Environmental Pollution / Czech Republic / Molecular Epidemiology / Humans / Mutation / Polycyclic Aromatic Hydrocarbon / Carcinogens / Enzyme / Reviews / Comet Assay / Polycyclic aromatic hydrocarbons (PAHs) / Fluorescent In-Situ Hybridisation / Neoplasms / Particulate Matter / Biological markers / Environmental Pollutants / Oxidative Dna Damage / Genetic Susceptibility / Cancer Risk / Organic Compound / Environmental Exposure

Evaluación de los arándanos como radioprotectores potenciales

Radiation / Antioxidants / Comet Assay / Arándanos

JS-K, a GST-activated nitric oxide generator, induces DNA double-strand breaks, activates DNA damage response pathways, and induces apoptosis in vitro and in vivo in human multiple myeloma cells

Immunohistochemistry / DNA damage / Apoptosis / Cell Division / Cell line / Humans / Nitric oxide / Blood / Multiple Myeloma / Clinical Sciences / Comet Assay / Mouse Model / DNA damage response / Tumor Growth / Clinical evaluation / Insulin Like Growth Factor / Bone marrow stromal cells / DNA double strand breaks / Humans / Nitric oxide / Blood / Multiple Myeloma / Clinical Sciences / Comet Assay / Mouse Model / DNA damage response / Tumor Growth / Clinical evaluation / Insulin Like Growth Factor / Bone marrow stromal cells / DNA double strand breaks
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